Related Experiment Video
Updated: Sep 8, 2025
08:54
Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
1.2K
Intelligent Supramolecular Nanoprodrug Based on Anionic Water-Soluble [2]Biphenyl-Extended-Pillar[6]arenes for
Yue Ding1, Wei Yu1, Jian Wang1
1School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, People's Republic of China.
ACS Macro Letters
|June 14, 2022
Abstract:
An anionic water-soluble [2]biphenyl-extended-pillar[6]arenes modified with eight ammonium salt ions (AWBpP6) was successfully synthesized to establish a drug-drug conjugate supramolecular nanoprodrug (SNP) with a high drug-loading capacity. This SNP can generate a synergistic triple therapeutic effect of photodynamic therapy (PDT), photothermal therapy (PTT), and chemotherapy (CT; i.e., PDT-PTT-CT) with excellent biocompatibility.
