Prehospital Care of Coronary Artery Disease and Its Major Risk Factors in Geropsychiatric Inpatients
Peter Manu1,2, Eugene Grudnikoff2,3, Dan A Constantin4
1Department of Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.
Insights
Older adults in psychiatric care with dementia showed better control of heart disease risk factors like high blood pressure, cholesterol, and diabetes compared to those with mood or psychotic disorders.
Area of Science:
- Geriatric Psychiatry
- Cardiology
- Internal Medicine
Background:
- Older adults with serious mental illness often have high rates of coronary artery disease and its risk factors.
- Clinical control of these conditions has not been compared between geropsychiatric inpatients with dementia versus those with mood or psychotic disorders.
Purpose of the Study:
- To determine the prevalence and control of coronary artery disease, arterial hypertension, dyslipidemia, and diabetes mellitus in patients receiving geropsychiatric care.
- To compare these cardiometabolic conditions among patients with dementia, mood disorders, and psychotic disorders.
Main Methods:
- A cohort of 689 patients aged 65+ admitted to a geropsychiatric unit over 3 years was analyzed.
- Structured clinical and laboratory evaluations were performed within 72 hours of admission.
- Primary psychiatric diagnoses, medical history, and cardiometabolic comorbidity requiring management changes were assessed.
Main Results:
- A significant proportion of patients had poorly controlled arterial hypertension (51.2%), dyslipidemia (25.4%), diabetes (24.2%), and coronary artery disease (15.4%).
- Patients with dementia exhibited a lower prevalence of poorly controlled dyslipidemia, diabetes, and coronary artery disease compared to those without dementia.
- While the number of medical conditions was similar, dementia patients showed better control of specific cardiometabolic issues.
Conclusions:
- Dementia with behavioral disturbance in geropsychiatric inpatients was associated with better control of coronary artery disease, dyslipidemia, and diabetes mellitus.
- This suggests a potential difference in cardiometabolic risk factor management or presentation based on primary psychiatric diagnosis in older adults.
Background:
Older adults with serious mental illness have a high prevalence of coronary artery disease and of its major risk factors, that is, arterial hypertension, dyslipidemia, and diabetes mellitus. The prevalence and clinical control of these conditions have not been compared in geropsychiatric inpatients with dementia versus those with mood or psychotic disorders.
Study Question:
What is the prevalence and acuity of coronary artery disease, arterial hypertension, dyslipidemia, and diabetes mellitus among patients with dementia, mood, and psychotic disorders admitted for geropsychiatric care?
Study Design:
Patients 65 years of age or older were identified in a cohort of 1000 patients consecutively admitted over a 3-year period to the geropsychiatric unit of a 200-bed mental health hospital in suburban New York. All patients had a structured clinical and laboratory evaluation within 72 hours of admission.
Data Sources:
Primary psychiatric diagnoses, medical history, the frequency of poorly controlled cardiometabolic comorbidity requiring an immediate change in the management plan, and the Charlson Comorbidity Index (CCI).
Results:
The 65 years and older patient sample (N = 689) had a mean age of 74.8 years, and 58.8% of the subjects were women. The 205 patients with dementia were older ( P < 0.001) than the 337 patients with mood disorders and the 147 patients with psychotic syndromes. The numbers of medical conditions and the CCI after exclusion of dementia were similar in patients with dementia versus patients without dementia. A substantial number of patients had poorly controlled arterial hypertension (51.2%), dyslipidemia (25.4%), diabetes (24.2%), and coronary artery disease (15.4%). Patients with dementia had a lower prevalence of poorly controlled dyslipidemia ( P = 0.0006), diabetes ( P = 0.0089), and coronary artery disease ( P = 0.045).
Conclusions:
Compared with mood or psychotic disorder, a diagnosis of dementia with behavioral disturbance seemed to be associated with better control of coronary artery disease, dyslipidemia, and diabetes mellitus in geropsychiatric inpatients.
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