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Published on: September 20, 2018
[Infective endocarditis in pregnancy: A case report]
1Department of Gynecology and Obstetrics, Peking University Third Hospital, Beijing 100191, China.
Infective endocarditis in pregnancy is rare but dangerous, risking maternal and fetal health. This case highlights successful combined surgical intervention for a pregnant patient with severe mitral valve vegetation.
Area of Science:
- Cardiology
- Obstetrics
- Infectious Diseases
Background:
- Infective endocarditis (IE) in pregnancy is rare, with limited guidelines and scarce case reports.
- Pregnancy-related hemodynamic changes increase risks of embolism, cardiac arrest, and fetal distress from IE.
- IE poses significant threats to both maternal and fetal survival, necessitating careful management.
Observation:
- A 30-week pregnant patient presented with severe symptoms of IE, including cardiac insufficiency and large mitral valve vegetation.
- Initial antibiotic treatment for Staphylococcus epidermidis infection was ineffective.
- Imaging revealed significant mitral valve vegetation and severe regurgitation, suggesting perforation.
Findings:
- A multidisciplinary team performed a combined cardiac surgery and obstetrics operation.
- The procedure involved 60 minutes of cardiac arrest and 1200 mL blood loss.
- Both mother and newborn had favorable outcomes, with the newborn experiencing mild asphyxiation at birth.
Implications:
- This case underscores the critical need for early diagnosis and individualized treatment strategies for IE in pregnancy.
- Successful outcomes depend on effective interdisciplinary communication and collaboration among specialists.
- Prompt, combined surgical intervention can significantly improve prognosis in complex IE cases during gestation.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Mitral Valve Prolapse III: Nursing Management
Rheumatic Heart Disease I: Introduction

