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Endovascular treatment of intracranial aneurysms using the Derivo Embolization Device: a multicenter experience

Galileu Chagas Lourenço1, François Dantas2, Tiago Silva E Carvalho2

  • 1Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil galileucl@gmail.com.

Journal of Neurointerventional Surgery
|June 15, 2022
PubMed

Insights

The Derivo Embolization Device is a safe and effective treatment for intracranial aneurysms, showing high occlusion rates and minimal adverse events in a 1-year follow-up study.

Area of Science:

  • Neurosurgery
  • Interventional Neuroradiology
  • Vascular Neurology

Background:

  • Flow diversion is a primary treatment for various intracranial aneurysms.
  • The Derivo Embolization Device is utilized for treating these aneurysms.
  • A 1-year angiographic follow-up was conducted for patients treated with this device.

Purpose of the Study:

  • To evaluate the clinical and angiographic outcomes of intracranial aneurysm treatment using the Derivo Flow Diverter.
  • To determine the complete aneurysm occlusion rate at 12 months post-treatment.
  • To assess the incidence of serious adverse events associated with the device.

Main Methods:

  • Multicenter retrospective analysis of prospectively collected data.
  • Evaluation of complete aneurysm occlusion using digital subtraction angiography (DSA).
  • Logistic regression analyses were performed to identify predictors of outcomes.

Main Results:

  • The study included 127 patients with 177 intracranial aneurysms across three centers.
  • Total occlusion rate at 12 months was 83.3%, with a favorable occlusion rate of 97.7%.
  • 97.6% of patients experienced no serious adverse events, and no procedure-related mortality occurred.

Conclusions:

  • The Derivo Embolization Device demonstrates significant safety and efficacy in treating intracranial aneurysms.
  • High rates of total and favorable occlusion were achieved within 1 year.
  • The device is associated with minor morbidity and no intervention-related mortality.
Abstract

Keywords:
aneurysmflow diverterstentstroke

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