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Gatekeeping astrocyte identity

Alexis Cooper1,2, Benedikt Berninger1,2,3

  • 1Centre for Developmental Neurobiology, King's College London, London, United Kingdom.

Elife
|June 20, 2022
PubMed

Abstract:

New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.

Keywords:
PTBP1astrocyteastrocyte-to-neuron conversionbrain repairlineage reprogrammingmouseneuroscienceparkinson's diseaseregenerative medicinestem cells

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