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Updated: Sep 7, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
CONSTRUCT VALIDITY ANALYSIS OF THE GENETICS AND GENOMICS IN NURSING PRACTICE SURVEY: OVERCOMING CHALLENGES IN
Alexandra Plavskin1, William E Samuels2, Kathleen A Calzone3
1Hunter College, New York, NY, USA atsybesk@hunter.cuny.edu.
This study assessed the construct validity of the Genetics and Genomics Nursing Practice Survey (GGNPS). Results support its theory-based validity despite challenges from its response format.
Area of Science:
- Nursing Practice
- Genetics and Genomics
- Psychometrics
Background:
- Assessing the validity of nursing practice surveys is crucial for evidence-based practice.
- The Genetics and Genomics Nursing Practice Survey (GGNPS) requires rigorous evaluation of its psychometric properties.
Purpose of the Study:
- To evaluate the construct validity of the GGNPS.
- To investigate the factorial structure of the GGNPS, accounting for response variations.
- To determine the most appropriate factor model for the GGNPS.
Main Methods:
- Exploratory and confirmatory factor analyses were employed.
- Structural equation modeling (SEM) was used to assess model fit.
- Common methods bias analyses were conducted to evaluate construct validity.
Main Results:
- A 7-factor model demonstrated a slightly better fit (RMSEA = .052) compared to a 5-factor model (RMSEA = .063).
- Fit indices like CFI and TLI did not meet conventional thresholds, indicating structural limitations.
- The survey's response format presented challenges for construct validity assessment.
Conclusions:
- Despite response format challenges, the study supports the theory-based construct validity of the GGNPS.
- Further refinement may be needed to optimize the GGNPS for robust psychometric evaluation.
- The findings contribute to the understanding of genetic and genomics nursing competencies.
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