CONSTRUCT VALIDITY ANALYSIS OF THE GENETICS AND GENOMICS IN NURSING PRACTICE SURVEY: OVERCOMING CHALLENGES IN VARIABLE RESPONSE INSTRUMENTS
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Updated: Sep 7, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Alexandra Plavskin1, William E Samuels2, Kathleen A Calzone3
1Hunter College, New York, NY, USA atsybesk@hunter.cuny.edu.
Abstract:
Background and Purpose: We evaluated the construct validity of the Genetics and Genomics Nursing Practice Survey by investigating the factoral structure, while attempting to account for varied response structures of the items. Methods: Exploratory factor analyses provided insights into item loadings. Confirmatory factor analyses and a version of common methods bias analyses evaluated construct validity while considering the instrument's structural limitations. Structural equation models provided information regarding model fit. Results: The 7-factor model fit these data slightly better (AIC ≈ 169,405; RMSEA = .052) than did the 5-factor model (AIC ≈ 183,599; RMSEA = .063). Neither the CFI or TLI met commonly-accepted thresholds for adequate model fits. Conclusion: The response format of the GGNPS created challenges in evaluating the instrument for construct validity. Nonetheless, these results support the theory-based construct validity of the GGNPS.
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