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Updated: Sep 7, 2025

Gold Nanoparticle Synthesis
Published on: July 10, 2021
Modulating the antibacterial activity of gold nanoparticles by balancing their monodispersity and aggregation
Le Wang1, Wenfu Zheng2, Sixiang Li1
1Guangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Rd, Nanshan District, Shenzhen, Guangdong, 518055, China. jiang@sustech.edu.cn.
Abstract:
Aggregation is a key factor influencing the function of nanoparticles. Thioproline-modified gold nanoparticles show potent antibacterial activity, which is compromised by thioproline-mediated particle aggregation. By tuning the balance between the exposure and shielding of thioproline, a maximal antibacterial property of the gold nanoparticles is achieved.

