[Age-related menopause and carbonyl stress.]

The review analyzes the literature data on studies of redox homeostasis in women with age-related physiological menopause. Despite the ambiguity of the presented results on the lipids, proteins, carbohydrates oxidative modification, most studies allow us to consider this age period as one of the factors in the carbonyl stress development, which is an integral part of aging. The presence of hyperglycemia and free radical pathology are presented as the main causes of the carbonyl stress development, age-related estrogen deficiency, taking into account their antioxidant properties, is considered as one of the triggers for this condition development, and the glutathione system is identified as one of its main inhibitors.