Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spreading of Chromatin Modifications02:25

Spreading of Chromatin Modifications

8.5K
The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
Writers
The writer...
8.5K
Histone Modification02:32

Histone Modification

13.8K
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
13.8K
Duplication of Chromatin Structure02:05

Duplication of Chromatin Structure

5.7K
The process of chromosome duplication during cell division requires genome-wide disruption and re-assembly of chromatin. The chromatin structure must be accurately inherited, reassembled, and maintained in the daughter cells to ensure lineage propagation.
The basic unit of the chromatin is the nucleosome, consisting of DNA wrapped around octameric histone proteins and short stretches of linker DNA separating individual nucleosomes. The histone proteins within the nucleosome have their...
5.7K
Chromatin Structure and RNA Splicing02:41

Chromatin Structure and RNA Splicing

2.8K
2.8K
Chromatin Packaging02:21

Chromatin Packaging

8.4K
8.4K
Euchromatin01:01

Euchromatin

2.9K
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rtt107 cooperates with Rad55 to limit specific types of genome instability in Saccharomyces cerevisiae.

DNA repair·2026
Same author

Functional divergence of TBP homologs through distinct DNA-binding dynamics.

Nucleic acids research·2025
Same author

Dynamic regulation of murine RNA polymerase III transcription during heat shock stress.

Genetics·2025
Same author

Human MeCP2 binds to promoters and inhibits transcription in an unmethylated yeast genome.

Genetics·2025
Same author

TBP facilitates RNA Polymerase I transcription following mitosis.

RNA biology·2024
Same author

A dynamic role for transcription factors in restoring transcription through mitosis.

Biochemical Society transactions·2024

Related Experiment Video

Updated: Sep 7, 2025

Chromatin Immunoprecipitation in the Cnidarian Model System Exaiptasia diaphana
11:48

Chromatin Immunoprecipitation in the Cnidarian Model System Exaiptasia diaphana

Published on: March 17, 2023

534

43rd International Asilomar Chromatin, Chromosomes, and Epigenetics Conference.

Joshua A R Brown1, Jieying Hazel Cui1, Maggie Y M Ling1

  • 1Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
|June 21, 2022
PubMed
Summary

The 43rd Asilomar Chromatin, Chromosomes, and Epigenetics Conference showcased new chromatin research findings. Experts discussed nuclear organization, transcription regulation, and human disease mechanisms.

Keywords:
chromatinchromatinechromosomesepigeneticstranscriptionépigénétique

More Related Videos

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

10.5K
Capturing Chromosome Conformation Across Length Scales
10:15

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

3.6K

Related Experiment Videos

Last Updated: Sep 7, 2025

Chromatin Immunoprecipitation in the Cnidarian Model System Exaiptasia diaphana
11:48

Chromatin Immunoprecipitation in the Cnidarian Model System Exaiptasia diaphana

Published on: March 17, 2023

534
An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

10.5K
Capturing Chromosome Conformation Across Length Scales
10:15

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

3.6K

Area of Science:

  • Molecular Biology
  • Genetics
  • Cell Biology

Background:

  • The Asilomar Conference is a key event in chromatin research.
  • The 2021 conference focused on recent advancements in the field.
  • Chromatin, chromosomes, and epigenetics are crucial for understanding cellular function and disease.

Purpose of the Study:

  • To disseminate novel findings in chromatin, chromosomes, and epigenetics.
  • To foster discussion on fundamental principles and disease mechanisms.
  • To provide a platform for researchers at various career stages.

Main Methods:

  • Presentations of new research findings.
  • Keynote lectures by diverse experts.
  • Discussions on modern chromatin research across model systems.

Main Results:

  • Sharing of promising new discoveries in chromatin biology.
  • Exploration of topics from nuclear organization to human disease.
  • Broad coverage of epigenetics and chromosome dynamics.

Conclusions:

  • The conference successfully highlighted cutting-edge research in chromatin, chromosomes, and epigenetics.
  • Advancements in understanding gene regulation and disease mechanisms were presented.
  • The online format facilitated broad participation and knowledge sharing.