Related Experiment Video
Updated: Sep 7, 2025
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Impact of peripapillary retinoschisis on visual field test results in glaucomatous eyes
Ji-Ah Kim1, Eun Ji Lee2, Tae-Woo Kim3
1Department of Ophthalmology, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.
Insights
Peripapillary retinoschisis (PRS) does not significantly impact visual field (VF) test results in primary open-angle glaucoma (POAG) patients. VF testing remains a valuable tool for assessing glaucomatous damage, even with PRS presence.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Retinal Imaging
Background:
- Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
- Peripapillary retinoschisis (PRS) is a condition that can affect the optic nerve head in glaucoma patients.
- Understanding the impact of PRS on diagnostic tests is crucial for accurate glaucoma management.
Purpose of the Study:
- To determine the short-term influence of peripapillary retinoschisis (PRS) on visual field (VF) test outcomes.
- To assess the reliability of VF testing in primary open-angle glaucoma (POAG) patients with co-existing PRS.
Main Methods:
- A longitudinal study included 30 eyes of 30 POAG patients with at least one occurrence of PRS.
- Spectral-domain optical coherence tomography (OCT) was used to detect PRS.
- Visual field sensitivity was compared immediately before and after PRS formation or resolution over a minimum 5-year follow-up.
Main Results:
- No statistically significant differences were observed in global Mean Deviation (MD) or regional VF deviations before and after PRS formation.
- Similarly, global MD and regional VF deviations remained comparable before and after PRS resolution.
Conclusions:
- Peripapillary retinoschisis (PRS) does not appear to have a short-term effect on visual field (VF) sensitivity.
- VF testing remains a useful method for evaluating glaucomatous damage in POAG patients, even when PRS is present.
Background/Aims:
To investigate the influence of peripapillary retinoschisis (PRS) on visual field (VF) test results in patients with primary open angle glaucoma (POAG).
Methods:
Thirty eyes of 30 patients with POAG who had PRS at least once were included. All eyes were followed-up for a minimum 5 years at 4-6-month intervals. The occurrence of PRS was determined by circumpapillary retinal nerve fibre layer B-scan on spectral-domain optical coherence tomography (OCT). The global and regional VF deviations just prior to and immediately after PRS formation, or just prior to and immediately after PRS resolution (if it occurred), were compared. VF sensitivity within the region corresponding to the OCT sector where PRS occurred was determined according to the Garway-Heath map.
Results:
Global MD (p=0.345) and regional VF deviations (p=0.255) did not differ significantly between immediately after and just prior to PRS formation. Global MD (p=0.846) and regional VF deviations (p=0.758) were also similar between immediately after and just prior to PRS resolution.
Conclusion:
PRS has no short-term effect on the VF sensitivity. Therefore, VF test can still be useful for evaluating glaucomatous damage even in the presence of PRS compared with OCT.
