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Updated: Sep 7, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Octahydropyrimido[4,5-g]quinazoline-5,10-diones: their multicomponent synthesis, self-assembly on graphite and
Max Van Hoof1, Lize Bynens2, Brent Daelemans3
1Molecular Design and Synthesis, Department of Chemistry, KU Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium. wim.dehaen@kuleuven.be.
Abstract:
A green multicomponent synthesis of previously unreported octahydropyrimido[4,5-g]quinazoline-5,6-diones was developed from simple building blocks. These highly symmetrical compounds show strong propensity to self-assembled molecular network (SAMN) formation on highly oriented pyrolytic graphite. The SAMN type is easily tunable by changing molecular characteristics. The redox behavior was studied by cyclic voltammetery.
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