Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

33
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
33
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

200
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
200
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

539
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
539
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

35
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
35
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

139
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
139
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

85
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
85

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of ghrelin on insulin sensitivity and beta-cell function after sleeve gastrectomy.

American journal of physiology. Endocrinology and metabolism·2026
Same author

Laparoscopic bariatric surgery versus any non-surgical intervention for adolescents or adults with obesity: protocol for a systematic review with meta-analysis and trial sequential analysis of randomised clinical trials.

BMJ open·2026
Same author

Effects of Acute Iso- and Hypocaloric Carbohydrate Restriction on Liver Fat and Glucose and Lipid Metabolism.

The Journal of clinical endocrinology and metabolism·2025
Same author

Effect of ghrelin on glucose tolerance, gut hormones, appetite, and food intake after sleeve gastrectomy.

American journal of physiology. Endocrinology and metabolism·2024
Same author

Development of upper gastrointestinal cancer in patients with symptomatic gallstones, cholecystectomy, and sphincterotomy: A nationwide cohort study.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society·2022
Same author

[Acute diverticulitis can be treated without antibiotics].

Ugeskrift for laeger·2021

Related Experiment Video

Updated: Sep 7, 2025

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.1K

Antibiotics for uncomplicated diverticulitis.

Marie-Louise Dichman1, Steffen Jais Rosenstock2, Daniel M Shabanzadeh3

  • 1Department of Surgical Gastroenterology , Hvidovre University Hospital, Copenhagen, Denmark.

The Cochrane Database of Systematic Reviews
|June 22, 2022
PubMed
Summary

Antibiotics for uncomplicated acute diverticulitis show uncertain effects on complications and surgery. More research is needed to clarify the benefits of antibiotic treatment versus no antibiotics for this condition.

More Related Videos

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

669
Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
03:25

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

1.0K

Related Experiment Videos

Last Updated: Sep 7, 2025

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.1K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

669
Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
03:25

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

1.0K

Area of Science:

  • Gastroenterology
  • Clinical Medicine

Background:

  • Diverticulitis, a complication of diverticulosis, has traditionally been treated with antibiotics, assuming it is infectious.
  • Emerging evidence suggests diverticulitis may be inflammatory, questioning the routine use of antibiotics.

Purpose of the Study:

  • To systematically review randomized controlled trials (RCTs) on antibiotic treatment for uncomplicated acute diverticulitis.
  • To determine if antibiotics impact complication risk or the need for emergency surgery.

Main Methods:

  • Systematic literature search of multiple databases (CENTRAL, MEDLINE, Embase, ClinicalTrials.gov, WHO ICTRP) up to February 2021.
  • Included RCTs comparing antibiotics to no antibiotics, placebo, or different antibiotic regimens for radiologically confirmed left-sided uncomplicated acute diverticulitis.
  • Assessed risk of bias, extracted data using risk ratios (RRs) with 95% confidence intervals, and performed random-effects meta-analyses.

Main Results:

  • Three RCTs (1329 participants) comparing antibiotics to no antibiotics showed low-certainty evidence for minimal difference in short-term complications (RR 0.89; 95% CI 0.30-2.62).
  • Evidence suggested a potential reduction in emergency surgery within 30 days with no antibiotics (RR 0.47; 95% CI 0.13-1.71), though with considerable imprecision.
  • Other comparisons (single vs. double antibiotic therapy, short vs. long IV administration) involved few participants and yielded uncertain clinical effects due to low certainty and high risk of bias in some trials.

Conclusions:

  • The effect of antibiotics for uncomplicated acute diverticulitis remains uncertain regarding complications, emergency surgery, recurrence, and long-term outcomes.
  • The current evidence quality is low, with only three relevant RCTs available.
  • Further high-quality trials are necessary to establish definitive treatment guidelines and provide precise effect estimates.