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Nerve crossover techniques for urinary bladder reinnervation: animal and human cadaver studies
The Journal of Urology
|May 1, 1987
Summary
This study explores microneural reconstructive techniques for neurogenic bladder dysfunction. By connecting intercostal nerves to sacral roots, researchers aim to restore bladder control after spinal cord injury.
Area of Science:
- Neurosurgery
- Urology
- Regenerative Medicine
Background:
- Spinal pathway interruption causes neurogenic bladder dysfunction.
- Restoring central control to the decentralized bladder may regain function.
Purpose of the Study:
- To describe nerve crossover techniques for intraspinal intercostal nerve to sacral root connection.
- To evaluate feasibility for recentralizing the bladder via microneural reconstruction.
Main Methods:
- Anatomical study using human cadaver dissections.
- Described nerve crossover techniques for intraspinal connections.
- Compared techniques to animal models with extradural root grafts.
Main Results:
- Detailed description of intraspinal nerve crossover techniques.
- Demonstrated feasibility in human cadavers.
- Built upon prior animal model success in cats.
Conclusions:
- Microneural reconstructive techniques offer a potential strategy for neurogenic bladder.
- Further laboratory studies are needed to confirm functional recovery.
- Selected patients may benefit from these bypass techniques for spinal cord lesions.