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Clinical application of extracorporeal shock wave lithotripsy using microexplosions
The Journal of Urology
|May 1, 1987
Summary
This study shows that using chemical explosives to create shock waves for upper urinary tract stone disintegration is effective, with 82% of patients stone-free after treatment. The method proved safe for clinical use.
Area of Science:
- Urology
- Nephrology
- Medical Engineering
Background:
- Upper urinary tract stones affect a significant patient population.
- Current stone disintegration methods have limitations.
- Novel approaches for extracorporeal stone disintegration are needed.
Purpose of the Study:
- To evaluate the efficacy and safety of extracorporeal stone disintegration using chemical explosive-generated shock waves.
- To assess the stone-free rate and complication profile of this novel lithotripsy technique.
Main Methods:
- A prototype disintegrator utilizing 10 mg of lead azide as an energy source for underwater shock waves was employed.
- 105 patients aged 11-72 years with upper urinary tract stones were treated.
- Follow-up assessment for stone-free status was conducted 3 months post-treatment.
Main Results:
- An overall stone-free rate of 82% was achieved 3 months after treatment.
- Shock wave therapy alone was successful in 73% of patients; others required adjunctive procedures.
- Common complications included colic pain (30%) and fever (23%); rare complications were managed conservatively.
Conclusions:
- Extracorporeal stone disintegration utilizing chemical explosive-generated shock waves is a safe and effective method for treating upper urinary tract stones.
- This technique offers a viable alternative for stone management, with a high stone-free rate and manageable complications.