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When blockchain meets artificial intelligence: An application to cancer histopathology
1Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.
Cell Reports. Medicine
|June 22, 2022
Summary
Blockchain models outperformed local models in predicting molecular features from cancer images. Decentralized approaches show promise for molecular cancer diagnosis.
Area of Science:
- Oncology
- Computer Science
- Bioinformatics
Background:
- Accurate prediction of molecular features from histopathology images is crucial for cancer diagnosis and treatment.
- Current predictive models often rely on centralized data, posing challenges for data privacy and accessibility.
Purpose of the Study:
- To evaluate the efficacy of blockchain-based models compared to traditional local models for predicting molecular features in cancer histopathology.
- To assess the performance of decentralized machine learning models in the context of cancer molecular diagnosis.
Main Methods:
- Utilized blockchain technology to develop decentralized predictive models.
- Compared the performance of blockchain-based models against local and merged models using cancer histopathology images.
- Focused on predicting specific molecular features relevant to cancer.
Main Results:
- Blockchain-based models demonstrated superior performance compared to local models.
- Decentralized models achieved performance comparable to merged models, indicating robustness and scalability.
- The study confirmed the potential of blockchain in enhancing molecular diagnosis accuracy.
Conclusions:
- Blockchain-based decentralized models are a viable and effective alternative for predicting molecular features from histopathology images.
- The findings support the integration of blockchain technology into cancer diagnostics for improved accuracy and data security.
- Decentralized approaches offer a promising future for molecular cancer diagnosis.

