Related Experiment Video
Updated: Sep 7, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
Schools under mandatory testing can mitigate the spread of SARS-CoV-2
Marc Diederichs1, Reyn van Ewijk1, Ingo E Isphording2,3
1Department of Economics, Johannes Gutenberg-University Mainz, 55128 Mainz, Germany.
School reopenings in Germany after summer 2021, coupled with mandatory testing, helped contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Open schools can aid in virus containment, making closures a last resort.
Area of Science:
- Epidemiology
- Public Health
- Virology
Background:
- The COVID-19 pandemic necessitated various public health interventions, including school closures and reopenings.
- Understanding the impact of school operations on viral transmission is crucial for effective pandemic management.
Purpose of the Study:
- To estimate the effect of school reopenings post-summer 2021 on the spread of SARS-CoV-2 in Germany.
- To evaluate the role of mandatory rapid testing in schools for viral containment.
Main Methods:
- Event study models utilizing staggered summer vacation schedules across German counties.
- Analysis of daily confirmed SARS-CoV-2 infection counts.
- Comparison of infection growth rates between states with reopened schools and control states.
Main Results:
- A short-term increase in detected infections post-reopening, attributed to uncovering asymptomatic cases via mandatory testing.
- Reduced case growth rates approximately two weeks after school reopenings compared to states still on break.
- Similar patterns observed in older age groups, suggesting effective cluster detection through school testing.
Conclusions:
- Mandatory rapid testing in schools can contribute to containing SARS-CoV-2 spread.
- Open schools, under specific conditions, can play a role in virus containment.
- School closures may have unintended consequences by reducing surveillance and should be a last resort measure.
More Related Videos
11:11Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
Published on: February 11, 2022
07:13Swabbing the Urban Environment - A Pipeline for Sampling and Detection of SARS-CoV-2 From Environmental Reservoirs
Published on: April 9, 2021