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Yolk Sac Tumor of the Cervix in an Infant: A Surgical Dilemma
Swati Narasimhan1, Janani Arul2, Rajendran Swaminathan3
1Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Insights
A rare yolk sac tumor of the uterine cervix in a 5-month-old infant achieved complete remission with chemotherapy alone. This case highlights the potential to avoid surgery in select pediatric gynecologic oncology patients.
Area of Science:
- Gynecologic Oncology
- Pediatric Oncology
- Rare Pediatric Tumors
Background:
- Yolk sac tumors (YSTs) are rare germ cell tumors.
- Cervical YSTs are exceptionally uncommon, particularly in infants.
- Management typically involves radical surgery, especially in pediatric cases.
Observation:
- A 5-month-old infant presented with vaginal bleeding.
- Diagnostic imaging revealed a yolk sac tumor of the uterine cervix.
- The patient's clinical presentation was atypical for this diagnosis due to extreme youth.
Findings:
- The infant received chemotherapy as the primary treatment modality.
- Complete remission was achieved following the chemotherapy regimen.
- Surgical intervention was successfully avoided in this case.
Implications:
- This case demonstrates the feasibility of non-surgical management for cervical yolk sac tumors in infants.
- Chemotherapy can be an effective alternative to surgery, preserving fertility and reducing morbidity.
- Highlights the importance of considering conservative treatment options in pediatric gynecologic malignancies.
Abstract:
A 5-month-old child presented with vaginal bleeding and found yolk sac tumor of the uterine cervix. She attained complete remission only with chemotherapy and on follow-up for more than a year. We report this for the unusual age and feasibility of avoiding surgery in selected cases.
