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Updated: Aug 18, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Unilateral Transient Enhanced SEP during Integrated Multiparameter Neurophysiological Monitoring in a Newborn with
Sara Cavaliere1, Silvia Lori2, Maria Bastianelli2
1Department of Neurosciences, Psychology, Drug Research and Children's Health, University of Florence, 50134 Florence, Italy.
Abstract:
During Integrated Multiparametric Neurophysiological Monitoring (IMNA), a newborn with suspected hypoxia at birth and microhaemorrhagic and ischaemic lesions presented some clonic-tonic episodes with specific EEG patterns characterized by rolandic and temporal spikes and the appearance of a unilateral enhanced Somatosensory Evoked Potential (SEP) (10.45 µv). Since the literature does not seem to describe cases of giant SEP in newborns, in this case report, we will discuss the hypotheses underlying this potential. It could be assumed that the ischaemic and haemorrhagic lesions presented by the newborn may have developed as a result of neurotransmitter balance failure. This may be the origin of the EEG picture, which, consequently, could have triggered a potential with high amplitude.
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