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Updated: Sep 6, 2025
10:44
Influenza A Virus Studies in a Mouse Model of Infection
Published on: September 7, 2017
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Embracing the heterogeneity of natural viruses in mouse studies
Jessica K Fiege1, Ryan A Langlois1
1Department of Microbiology and Immunology and the Center for Immunology, University of Minnesota, Minneapolis, USA.
The Journal of General Virology
|June 23, 2022
Abstract:
Animal models are a critical tool in modern biology. To increase reproducibility and to reduce confounding variables modern animal models exclude many microbes, including key natural commensals and pathogens. Here we discuss recent strategies to incorporate a natural microbiota to laboratory mouse models and the impacts the microbiota has on immune responses, with a focus on viruses.
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