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Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
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Current knowledge on spinal meningiomas: a systematic review protocol.

Victor Gabriel El-Hajj1,2, Jenny Pettersson Segerlind3,2, Gustav Burström3,2

  • 1Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden victor.gabriel.elhajj@stud.ki.se.

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Summary

This systematic review synthesizes current knowledge on spinal meningiomas, rare tumors of the meninges. It aims to improve understanding and management by evaluating epidemiology, diagnostics, and treatment outcomes from recent literature.

Keywords:
neurological oncologyneurosurgeryoncologyspine

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Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Oncology

Background:

  • Spinal meningiomas are primary central nervous system tumors arising from the meninges, less common than cranial counterparts.
  • Limited literature and attention are given to spinal meningiomas, necessitating systematic reviews for evidence-based strategies.
  • Current knowledge on spinal meningiomas requires summarization to enhance clinical understanding and treatment approaches.

Purpose of the Study:

  • To conduct a systematic literature review assessing spinal meningiomas.
  • To evaluate epidemiology, diagnostics, treatment modalities, and patient outcomes for spinal meningiomas.
  • To provide a structured summary of current evidence to aid clinical decision-making and identify research gaps.

Main Methods:

  • Systematic search of PubMed, Web of Science, and Embase for English studies published after 2000 using keywords 'spinal' and 'meningioma'.
  • Exclusion of case reports, editorials, letters, and reviews; reference list searching included.
  • Screening by multiple reviewers to minimize bias, with results categorized and graded using the GRADE approach.

Main Results:

  • The review will categorize findings into epidemiology, histopathology, diagnostics, surgical and non-surgical treatments, outcomes, and recurrence.
  • Evidence grading will be applied to provide a structured summary of current knowledge.
  • Identification of areas lacking sufficient research will be a key outcome.

Conclusions:

  • This systematic review will consolidate current knowledge on spinal meningiomas.
  • Findings aim to improve the understanding and management of spinal meningiomas.
  • The review will support clinical decision-making and guide future research directions.