Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

738
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
738
Plasticity00:58

Plasticity

2.5K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
2.5K
Lateralization01:28

Lateralization

449
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
449
Biological Influences on Intelligence01:30

Biological Influences on Intelligence

198
Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
198
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

567
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
567

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A single-echo/multi-echo BOLD fMRI test-retest dataset.

Data in brief·2026
Same author

Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Cascading Periods of Language-Related Brain Plasticity Across Early Childhood.

Developmental science·2026
Same author

Improved, rapid fetal-brain localization and orientation detection for auto-slice prescription.

Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition·2026
Same author

Fast, automated slice prescription of standard anatomical planes for fetal brain MRI.

Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition·2026
Same author

An open, fully-processed data resource for studying mood and sleep variability in the developing brain.

Aperture neuro·2026

Related Experiment Video

Updated: Sep 6, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K

Individual differences in frontoparietal plasticity in humans.

Austin L Boroshok1, Anne T Park2, Panagiotis Fotiadis3

  • 1Department of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA. boroshok@sas.upenn.edu.

NPJ Science of Learning
|June 23, 2022
PubMed
Summary

Neuroplasticity, the brain's ability to change, was examined using functional connectivity and myelin maps. Stronger ventral tegmental area (VTA) connectivity predicted better accuracy, while lower myelin predicted faster response times in learning tasks.

More Related Videos

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.3K

Related Experiment Videos

Last Updated: Sep 6, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.3K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neuroimaging

Background:

  • Neuroplasticity, the brain's capacity to adapt, is well-studied at cellular levels.
  • Animal models indicate ventral tegmental area (VTA) stimulation boosts plasticity and myelination constrains it.
  • Human brain correlates of these plasticity markers and their link to learning remain unclear.

Purpose of the Study:

  • To investigate frontoparietal system plasticity in humans.
  • To determine if VTA resting-state functional connectivity and myelin map values predict learning.
  • To assess the association between neural plasticity markers and cognitive performance.

Main Methods:

  • Recruited 46 healthy adults (ages 18-25).
  • Utilized resting-state functional connectivity and myelin map (T1w/T2w ratio) imaging.
  • Assessed learning on an adaptive n-back task before and after short-term training.

Main Results:

  • Greater VTA to lateral prefrontal cortex connectivity correlated with improved accuracy.
  • Lower myelin map values predicted faster response times, but not accuracy changes.
  • Findings suggest neural plasticity markers predict human learning outcomes.

Conclusions:

  • Proxy measures of neural plasticity, specifically VTA connectivity and myelin, are associated with learning.
  • These findings advance our understanding of the neural basis of cognitive improvement.
  • Future research can explore these markers for predicting learning potential.