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  3. An Open, Fully-processed Data Resource For Studying Mood And Sleep Variability In The Developing Brain.
  1. Home
  3. An Open, Fully-processed Data Resource For Studying Mood And Sleep Variability In The Developing Brain.

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Related Experiment Video

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

An open, fully-processed data resource for studying mood and sleep variability in the developing brain.

Juliette B H Brook1,2,3, Taylor Salo1,2,3, Audrey C Luo1,2,3

  • 1Department of Psychiatry, University of Pennsylvania, Philadelphia, PA.

Aperture Neuro
|June 17, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

This study introduces an open neuroimaging dataset for adolescents and young adults, linking brain development, emotion regulation, and sleep patterns. The resource aims to advance understanding of mood, sleep, and brain changes during these critical life stages.

Keywords:
ASLEMAactigraphyadolescenceaffective instabilitydMRIdevelopmentemotion regulationfMRIsleep

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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Sleep Science

Background:

  • Adolescence and early adulthood are critical periods for brain development, marked by significant changes in emotion regulation and sleep patterns.
  • Existing research often lacks integrated datasets that simultaneously capture affective dynamics, sleep variations, and multimodal brain development measures.
  • Understanding the interplay between mood, sleep, and brain maturation is crucial for addressing mental health challenges during these developmental stages.

Purpose of the Study:

  • To introduce a novel, open-access data resource combining neuroimaging with detailed behavioral assessments in adolescents and young adults.
  • To facilitate research investigating the complex relationships between emotional regulation, sleep, and brain development.
  • To provide a continuously updated dataset for longitudinal studies on neurodevelopmental trajectories.

Main Methods:

  • Utilized advanced neuroimaging techniques including multi-echo functional MRI, compressed-sensing diffusion MRI, and arterial spin-labeled MRI.
  • Collected densely sampled behavioral data through ecological momentary assessment, actigraphy, cognitive testing, and clinical phenotyping focused on emotion regulation.
  • Recruited and characterized an initial cohort (n=10) of adolescents and young adults for the open data resource.

Main Results:

  • The study successfully established a protocol for collecting multimodal data on brain development, affect, and sleep in the target age group.
  • The initial release provides a foundational dataset for researchers to explore the intricate connections between neurobiology, behavior, and sleep.
  • Data is openly available without restrictions, promoting transparency and collaborative research.

Conclusions:

  • This open data resource represents a significant contribution to the study of adolescent and young adult neurodevelopment.
  • It will accelerate discoveries regarding the dynamic interplay of mood, sleep, and brain maturation.
  • The project aims to foster a deeper understanding of mental health during critical developmental periods.