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Related Experiment Video

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Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

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Persistent Postural-Perceptual Dizziness (PPPD) from Brain Imaging to Behaviour and Perception.

Patricia Castro^1,2,3, Matthew J Bancroft⁴, Qadeer Arshad⁵

¹Neuro-Otology Department, University College London Hospitals, London WC1E 6DG, UK.

|June 24, 2022

Summary

Persistent postural-perceptual dizziness (PPPD) is a common cause of chronic dizziness. Understanding its pathophysiology requires integrated measurement of behavior, perception, and brain function.

Keywords:

PPPD behaviour functional imaging perception persistent postural perceptual dizziness postural control vestibular net-works

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Last Updated: Sep 6, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

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Published on: August 4, 2022

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

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Published on: April 28, 2020

Experimental Methods to Study Human Postural Control

Experimental Methods to Study Human Postural Control

Published on: September 11, 2019

Area of Science:

Neuroscience
Clinical Neurology
Human Physiology

Background:

Persistent postural-perceptual dizziness (PPPD) is a prevalent cause of chronic dizziness and morbidity in neurology.
Patients exhibit altered balance control, postural muscle stiffening, and increased body sway.
Risk factors include anxiety, neuroticism, and visual dependence.

Purpose of the Study:

To explore the links between behavioral postural changes, perceptual abnormalities, and neuroimaging findings in PPPD.
To highlight the need for integrated methodologies in studying PPPD.
To advance understanding of PPPD pathophysiology.

Main Methods:

Investigating the relationship between behavioral postural changes and perceptual abnormalities.
Examining imaging correlates of postural dysfunction in PPPD.
Proposing an integrated approach to measure behavior, perception, and brain function concurrently.

Main Results:

PPPD involves maladaptive postural strategies following balance insults.
Behavioral and perceptual changes are measurable and linked to underlying neural mechanisms.
Integrated assessment is crucial for understanding PPPD.

Conclusions:

Understanding PPPD requires a multi-faceted approach.
Concurrent measurement of behavior, perception, and brain function is essential for elucidating PPPD pathophysiology.
This integrated methodology will improve diagnosis and treatment strategies for chronic dizziness.