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Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis
Guhyun Kang1, Soomin Son2, Young-Min Shin3
1Department of Pathology, Daehang Hospital, Seoul 06699, Korea.
Medicina (Kaunas, Lithuania)
|June 24, 2022
Summary
The estimated recurrence rate of uncomplicated diverticulitis (UCD) after the first episode is 0.129. Older age and higher body temperature are potential risk factors for UCD recurrence.
Area of Science:
- Gastroenterology
- Epidemiology
Background:
- Uncomplicated diverticulitis (UCD) is a common gastrointestinal condition.
- Understanding the recurrence of UCD after the initial episode is crucial for patient management.
Purpose of the Study:
- To conduct a meta-analysis to estimate the recurrence rate and identify risk factors for uncomplicated diverticulitis (UCD) following the first episode.
Main Methods:
- A systematic literature search and review of 27 eligible studies.
- Subgroup analyses were performed based on lesion location, medical treatment, follow-up duration, and geographic location.
- Meta-regression analysis was used to identify significant correlations.
Main Results:
- The overall estimated recurrence rate for UCD was 0.129 (95% CI 0.102-0.162).
- Recurrence rates differed by colon location (right: 0.092, left: 0.153) and were highest in the 1-2 year follow-up subgroup.
- Asian populations showed a significantly lower recurrence rate (0.092) compared to non-Asian populations (0.147).
- Older age and higher body temperature were significantly correlated with UCD recurrence, while medications showed no significant correlation.
Conclusions:
- This meta-analysis provides detailed estimates of UCD recurrence rates.
- Older age and elevated body temperature are identified as potential risk factors for UCD recurrence after an initial episode.
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