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Osmoregulation in Fishes02:32

Osmoregulation in Fishes

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When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?
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Related Experiment Video

Updated: Sep 6, 2025

Design and Use of an Apparatus for Quantifying Bivalve Suspension Feeding at Sea
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Cellular Aquaculture: Prospects and Challenges.

Mukunda Goswami1, Yashwanth Belathur Shambhugowda1, Arjunan Sathiyanarayanan1

  • 1ICAR-Central Institute of Fisheries Education, Mumbai 400061, India.

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|June 24, 2022
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Cellular aquaculture offers a sustainable solution to meet rising fish demand. Developing and characterizing fish muscle cell lines is crucial for advancing this climate-resilient food production system.

Keywords:
aquaculturecultivated seafoodfuture food

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Area of Science:

  • Aquaculture and cellular biology
  • Sustainable food production

Background:

  • Aquaculture is vital for global food security, but faces challenges in meeting increasing fish demand.
  • Cellular aquaculture presents a climate-resilient alternative for producing quality fish.
  • Developing fish muscle cell lines is essential for advancing cellular aquaculture.

Purpose of the Study:

  • To highlight the importance of developing and characterizing fish muscle cell lines for cellular aquaculture.
  • To address the current limitations in teleost muscle cell line research compared to mammalian models.
  • To outline the requirements for successful cell-based aquaculture, including cell line development, optimization, and mass production.

Main Methods:

  • Review of existing research on muscle cell lines in mammals and teleosts.
  • Identification of challenges and prospects for cellular aquaculture.
  • Emphasis on the need for characterization, cryopreservation, and bioreactor-based mass production of fish muscle cells.

Main Results:

  • Mammalian muscle cell lines (e.g., C2C12) are well-established for studying muscle growth.
  • Equivalent permanent teleost muscle cell lines are scarce and underutilized in cellular aquaculture.
  • The potential of cellular aquaculture is currently limited by the lack of developed and characterized fish muscle cell lines.

Conclusions:

  • Development and characterization of fish muscle cell lines are critical for cellular aquaculture.
  • Cryopreservation and mass cell production in bioreactors are necessary steps to overcome current challenges.
  • Advancing fish muscle cell line technology will support sustainable and resilient aquaculture practices.