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Current Progress and Future Perspectives on the Use of Bacillus clausii
Emilia Ghelardi1, Ana Teresa Abreu Y Abreu2, Christian Boggio Marzet3
1Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Microorganisms
|June 24, 2022
Summary
Bacillus clausii spores survive the human gut, offering health benefits. Research reveals its physiological, antimicrobial, and immunomodulatory effects, with potential for new therapeutic applications.
Area of Science:
- Microbiology
- Probiotics
- Human Health
Background:
- Bacillus clausii is a probiotic with spore-forming abilities.
- Spore formation ensures survival in the gastrointestinal tract.
- Its health benefits are less documented than other probiotics like Lactobacillus and Bifidobacterium.
Purpose of the Study:
- To review the physiological, antimicrobial, and immunomodulatory properties of Bacillus clausii.
- To assess the quality and safety of Bacillus clausii probiotics.
- To explore potential new therapeutic applications of Bacillus clausii.
Main Methods:
- Literature review of studies on Bacillus clausii.
- Analysis of physiological characteristics.
- Evaluation of antimicrobial and immunomodulatory effects.
- Assessment of quality and safety data.
Main Results:
- Bacillus clausii exhibits significant probiotic potential due to its spore-forming ability.
- It possesses antimicrobial and immunomodulatory properties.
- Biochemical investigations suggest novel health benefits beyond traditional probiotic functions.
Conclusions:
- Bacillus clausii is a safe and effective probiotic with diverse health benefits.
- Further research into its biochemical properties may unlock new therapeutic uses.
- Increased dissemination of its benefits is needed.
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