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Near-Infrared Spectroscopy as a Potential COVID-19 Early Detection Method: A Review and Future Perspective.

Muna E Raypah¹, Asma Nadia Faris², Mawaddah Mohd Azlan²

¹School of Physics, Universiti Sains Malaysia, George Town 11800, Pulau Pinang, Malaysia.

Sensors (Basel, Switzerland)

|June 24, 2022

Summary

Near-infrared spectroscopy (NIRS) offers a rapid, non-invasive method for detecting viruses. This review explores NIRS

Keywords:

COVID-19 SARS-CoV-2 chemometrics diagnostics near-infrared spectroscopy viruses

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Area of Science:

Virology
Spectroscopy
Medical Diagnostics

Background:

The COVID-19 pandemic, caused by SARS-CoV-2, has significant global health and economic impacts.
Rapid and cost-effective diagnostic methods are crucial for controlling viral spread.
Near-infrared spectroscopy (NIRS) is a versatile, non-invasive technique for sample analysis.

Purpose of the Study:

To review the historical and current applications of NIRS in virology.
To evaluate the potential of NIRS as a novel diagnostic tool for SARS-CoV-2.
To highlight the advantages of NIRS, including its speed, low cost, and non-invasive nature.

Main Methods:

Review of existing literature on NIRS applications in virology.
Analysis of NIRS capabilities for chemical and physical structure profiling.
Exploration of NIRS integration with Internet of Things (IoT) for disease management.

Main Results:

NIRS has been successfully applied to detect various viruses, including Zika, chikungunya, influenza, hepatitis C, dengue, and HIV.
Advancements in NIRS instrumentation and spectral analysis have enhanced its medical applications.
NIRS offers a promising alternative for rapid and low-cost viral detection.

Conclusions:

NIRS demonstrates significant potential as a diagnostic technique for SARS-CoV-2.
The integration of NIRS with IoT can improve disease control and treatment strategies.
NIRS represents a valuable tool in the ongoing fight against viral pandemics.