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Published on: July 16, 2020
Ultrasound as a Neurotherapeutic: A Circuit- and System-Based Interrogation
Norman M Spivak1, William Jamie Tyler1, Ausaf A Bari1
1UCLA-Caltech Medical Scientist Training Program (Spivak), Department of Neurosurgery, David Geffen School of Medicine (Spivak, Bari), and Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior (Spivak, Kuhn), University of California, Los Angeles; School of Biological and Health Systems Engineering, Arizona State University, Tempe (Tyler).
Abstract:
Focused ultrasound is a novel brain stimulation modality that combines the noninvasiveness of repetitive transcranial magnetic stimulation and the precision of deep brain stimulation. In this review, the authors examine low-intensity focused ultrasound for brain mapping and neuromodulation. They also discuss high-intensity focused ultrasound, which is used for incisionless surgeries, such as capsulotomies for obsessive-compulsive disorder. Future potential applications of focused ultrasound are also presented.
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