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An Eye-Opening Presentation of Syphilis
Natalie Torrente1, Jorge Verdecia2, Michael Sands2
1Internal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Cureus
|June 24, 2022
Summary
This case report details a syphilis infection presenting as eye inflammation in an HIV-negative individual. Early diagnosis and treatment of syphilitic anterior uveitis led to significant vision improvement.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neurology
Background:
- Syphilis, a complex sexually transmitted infection, can manifest with diverse clinical presentations.
- Neurosyphilis, a late-stage complication, can affect various organ systems, including the eyes.
- Ocular syphilis is a known but often underdiagnosed manifestation of the disease.
Observation:
- A case of an HIV-negative patient presenting with unilateral eye redness and decreased vision.
- The patient's symptoms were initially non-specific, mimicking other ocular inflammatory conditions.
- Ophthalmological examination revealed signs consistent with anterior uveitis.
Findings:
- Diagnosis of syphilitic anterior uveitis as a complication of neurosyphilis.
- Cerebrospinal fluid analysis and serological tests confirmed the diagnosis.
- The patient demonstrated a significant positive response to appropriate antibiotic therapy.
Implications:
- Highlights the importance of considering syphilis in the differential diagnosis of uveitis, even in HIV-negative patients.
- Emphasizes the potential for ocular involvement in neurosyphilis.
- Underscores the need for prompt diagnosis and treatment to prevent vision loss and systemic complications.
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