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Hepatic Hydrothorax: A Narrative Review.
Benjamin Pippard1, Malvika Bhatnagar1, Lisa McNeill2
1Department of Respiratory Medicine, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK.
Hepatic hydrothorax (HH), a serious pleural effusion in cirrhosis patients, has poor survival. Management requires a multidisciplinary approach, focusing on therapies like diuretics, shunts, and transplantation.
Area of Science:
- Pulmonology
- Hepatology
- Internal Medicine
Background:
- Hepatic hydrothorax (HH) is a significant complication of advanced liver disease.
- It presents as pleural effusion in cirrhosis patients without other cardiac or pulmonary causes.
- HH is associated with high morbidity and mortality, with a median survival of 8-12 months.
Purpose of the Study:
- To provide a comprehensive narrative review of hepatic hydrothorax.
- To discuss its epidemiology, pathophysiology, clinical features, and management strategies.
- To highlight current therapeutic options and areas needing further research.
Main Methods:
- This is a narrative review based on existing literature.
- The review synthesizes information on HH from various sources.
- It focuses on established and emerging management strategies.
Main Results:
- Diagnosis of HH occurs in advanced liver disease with ascites, excluding other causes.
- Management is often based on expert opinion due to limited large-scale trials.
- Therapeutic options include salt restriction, diuretics, shunts, liver transplantation, pleural interventions, and palliative care.
Conclusions:
- Hepatic hydrothorax necessitates a multidisciplinary approach involving various specialists.
- Optimal management strategies are still evolving, with a need for more robust clinical trials.
- Palliative care plays a vital role in patient-centered management of HH.
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