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Related Concept Videos

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

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The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
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Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Nursing Assessment of the Genitourinary System III: Percussion and Auscultation01:22

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The genitourinary system maintains the body's fluid balance, waste excretion, and overall homeostasis. Proper assessment is essential for early detection of disorders, with percussion and auscultation integral to this evaluation. These methods help identify signs of kidney or bladder issues and provide important diagnostic clues.Percussion for Kidney TendernessPercussion is used to assess tenderness and detect kidney and bladder abnormalities. A common method for determining kidney tenderness...
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Acute Kidney Injury I: Introduction01:22

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Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
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SPR-Based Sensor for the Early Detection or Monitoring of Kidney Problems.

Budi Mulyanti1, Harbi Setyo Nugroho2, Chandra Wulandari2,3

  • 1Department of Electrical Engineering Education, Universitas Pendidikan Indonesia, Bandung 40154, Jawa Barat, Indonesia.

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Summary

Surface Plasmon Resonance (SPR) sensors offer real-time, label-free detection for kidney disease biomarkers. This review highlights SPR advancements for monitoring kidney health and related analytes.

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Nanotechnology

Background:

  • Kidney disease is a major global health concern with significant morbidity and mortality.
  • Current diagnostic methods require improvement for early and accurate detection.
  • Sensor technology plays a crucial role in advancing kidney disease monitoring.

Purpose of the Study:

  • To provide a comprehensive review of Surface Plasmon Resonance (SPR) based sensors for kidney disease detection.
  • To discuss recent advancements in SPR sensor technology for monitoring kidney-related health issues.
  • To highlight the broad applicability of SPR sensors in diagnosing kidney problems.

Main Methods:

  • Review of various SPR configurations including Kretschmann, Otto, optical fiber-based SPR, and Localized SPR (LSPR).
  • Analysis of SPR sensor applications for detecting key kidney disease biomarkers.
  • Synthesis of findings from recent studies on SPR sensor development for kidney health.

Main Results:

  • SPR technology offers real-time, label-free, and high-sensitivity detection of molecular interactions.
  • SPR sensors are effective in detecting critical kidney disease biomarkers such as urea, creatinine, glucose, uric acid, and dopamine.
  • Various SPR configurations demonstrate significant potential for robust kidney disease monitoring.

Conclusions:

  • SPR-based sensors represent a versatile and promising tool for the early detection and monitoring of kidney diseases.
  • The continuous development of SPR technology facilitates improved diagnostic capabilities for kidney-related conditions.
  • This review underscores the potential of SPR sensors to advance kidney health management and patient outcomes.