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Subcutaneous entomophthoramycosis in a child presenting as panniculitis: a case report from Bihar, India
Archana Archana1, Asmita Sinha2, Prathyusha Kokkayil1
1Department of Microbiology, All India Institute of Medical Sciences, Patna, Phulwarisarif, Bihar, India.
Insights
A rare fungal infection, subcutaneous entomophthoramycosis caused by Basidiobolus spp., was diagnosed in a child with persistent leg swelling. Early diagnosis and treatment with itraconazole and potassium iodide are crucial for managing this panniculitis-like condition.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Dermatology
Background:
- Subcutaneous entomophthoramycosis is a rare fungal infection.
- It can present with panniculitis-like symptoms, leading to diagnostic delays.
- Basidiobolus species are the causative agents.
Observation:
- A 5-year-old boy presented with a year of progressive, painful swelling of the lower limbs and buttocks.
- Initial misdiagnosis as non-infective panniculitis delayed appropriate treatment.
- Diagnosis was confirmed via KOH mount, fungal culture, and slide culture of aspirated pus.
Findings:
- The patient was diagnosed with subcutaneous entomophthoramycosis caused by Basidiobolus spp.
- Histopathological examination and fungal identification confirmed the diagnosis.
- The patient showed a positive response to oral itraconazole and potassium iodide therapy.
Implications:
- This case highlights the importance of considering rare fungal infections in differential diagnoses.
- Prompt and accurate diagnosis is essential for effective management of subcutaneous entomophthoramycosis.
- Timely treatment can prevent extensive disease progression and improve patient outcomes.
Abstract:
A 5-year-boy from Bihar, India was admitted to a tertiary care hospital with painful swelling over both lower limbs and buttocks, which had been increasing progressively for the past 1 year. The condition was initially undiagnosed and was later misdiagnosed as non-infective panniculitis, delaying treatment. Subsequently, the patient was diagnosed with subcutaneous entomophthoramycosis caused by Basidiobolus spp. A preliminary diagnosis was made by considering the history, clinical features, radiological findings and histopathological examination of the biopsied tissue. The confirmatory diagnosis was made using conventional techniques on aspirated pus, which included KOH wet mount and fungal culture on Sabouraud dextrose agar tubes incubated at 28°C and 37°C, respectively. Lactophenol cotton blue mount and slide culture were performed for identification of the fungal isolate. The patient responded well to oral itraconazole and oral potassium iodide. Delayed diagnosis and extensive involvement in a rare case of subcutaneous entomophthoramycosis causing panniculitis emphasizes the importance of correct diagnosis and appropriate, effective treatment.
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