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Related Experiment Video

Updated: Sep 6, 2025

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
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Morgellons Disease Treated as a Psychosomatic Condition.

Hunter A Cutlip1, Raja Mogallapu1, Michael Ang-Rabanes1

  • 1Psychiatry, West Virginia University School of Medicine, Martinsburg, USA.

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|June 27, 2022
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Summary

This case report describes a patient diagnosed with Morgellons disease after a diphenhydramine overdose. It highlights the lack of physical findings and reviews the psychosomatic aspects of this condition.

Keywords:
chronic lyme diseasedelusional parasitosismorgellons diseasepsychosomatic disorderspsychosomatic symptoms

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Area of Science:

  • Psychiatry
  • Dermatology
  • Medical Case Reports

Background:

  • This case report focuses on a patient presenting with a perceived skin condition leading to a diphenhydramine overdose.
  • The patient's history revealed prior consultations with Family Medicine and Dermatology for similar complaints.

Observation:

  • The patient described a condition causing significant life impairment, accompanied by psychiatric symptoms.
  • Despite extensive consultations, other medical specialties noted a lack of physical findings.

Findings:

  • The patient was diagnosed with Morgellons disease, a condition characterized by the patient's subjective experience and associated psychiatric symptoms.
  • This diagnosis was made considering the psychosomatic presentation and the absence of objective dermatological evidence.

Implications:

  • This case underscores the importance of considering psychosomatic factors in unexplained dermatological conditions.
  • It highlights the diagnostic challenges and the need for a multidisciplinary approach in managing patients with Morgellons disease.
  • Further research into the psychosomatic presentation of Morgellons disease is warranted.