Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prediction Intervals01:03

Prediction Intervals

2.3K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
2.3K
Interpretation of Confidence Intervals01:19

Interpretation of Confidence Intervals

6.5K
A confidence interval is a better estimate of the population than a point estimate, as it uses a range of values from a sample instead of a single value.
Confidence intervals have confidence coefficients that are crucial for their interpretation. The most common confidence coefficients are 0.90, 0.95, and 0.99, which can be written as percentages–90%, 95%, and 99%, respectively.
Suppose a person calculates a confidence interval with a confidence coefficient of 0.95. In that case, they can...
6.5K
Time-Domain Interpretation of PD Control01:07

Time-Domain Interpretation of PD Control

177
Proportional-Derivative (PD) control is a widely used control method in various engineering systems to enhance stability and performance. In a system with only proportional control, common issues include high maximum overshoot and oscillation, observed in both the error signal and its rate of change. This behavior can be divided into three distinct phases: initial overshoot, subsequent undershoot, and gradual stabilization.
Consider the example of control of motor torque. Initially, a positive...
177
Confidence Intervals01:21

Confidence Intervals

7.1K
An unbiased point estimate is often insufficient to predict a population estimate, such as population mean or population proportion. In this scenario, a confidence interval is used. A confidence interval is an estimate similar to a  sample proportion. However, unlike the point estimate which is a single value, the confidence interval  contains a range of values. These values have lower and upper limits, known as confidence limits, and can be designated as L1 and L2, respectively.
A...
7.1K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

171
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
171
Control Systems01:10

Control Systems

1.4K
Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In Science Journals.

Science (New York, N.Y.)·2026
Same author

Selective Antimicrobial Activity of Slightly Acidic Electrolyzed Water: Differential Effects on Harmful and Beneficial Bacteria in Microbial Fermentation Systems.

Environmental microbiology·2026
Same author

An Ene Reductase, KlebER1, for the Production of Dihydrocarvone: Identification, Characterization, Engineering, and Application.

Journal of agricultural and food chemistry·2026
Same author

Autofocusing optical-resolution photoacoustic microscopy.

Ultrasonics·2026
Same author

A Deep Learning-Based Correction for Scanning Radius Errors in Circular-Scan Photoacoustic Tomography.

Journal of imaging·2026
Same author

Real-World Effectiveness of Early Language Intervention: Evidence From a Nationwide Rollout of the Nuffield Early Language Intervention in England.

American journal of speech-language pathology·2026
Same journal

Instrumental Variable Estimation of Marginal Structural Mean Models for Time-Varying Treatment.

Journal of the American Statistical Association·2026
Same journal

Semiparametric Joint Modeling for Survival Analysis with Longitudinal Covariates.

Journal of the American Statistical Association·2026
Same journal

Dimension Reduction for Large-Scale Federated Data: Statistical Rate and Asymptotic Inference.

Journal of the American Statistical Association·2026
Same journal

Facilitating Heterogeneous Effect Estimation via Statistically Efficient Categorical Modifiers.

Journal of the American Statistical Association·2026
Same journal

Nonparametric Density Estimation of a Long-Term Trend from Repeated Semicontinuous Data.

Journal of the American Statistical Association·2026
Same journal

Functional Integrative Bayesian Analysis of High-dimensional Multiplatform Clinicogenomic Data.

Journal of the American Statistical Association·2026
See all related articles

Related Experiment Video

Updated: Sep 6, 2025

Synthetic Antigen Controls for Immunohistochemistry
09:30

Synthetic Antigen Controls for Immunohistochemistry

Published on: August 23, 2021

2.6K

Prediction Intervals for Synthetic Control Methods.

Matias D Cattaneo1, Yingjie Feng2, Rocio Titiunik3

  • 1Department of Operations Research and Financial Engineering, Princeton University.

Journal of the American Statistical Association
|June 27, 2022
PubMed
Summary
This summary is machine-generated.

We developed conditional prediction intervals for synthetic control (SC) methods to quantify uncertainty. Our approach provides finite-sample probability guarantees, accounting for SC weight construction and post-treatment errors.

Keywords:
causal inferencenon-asymptotic inferenceprediction intervalssynthetic controls

More Related Videos

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.7K
Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
20:24

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study

Published on: January 31, 2014

16.6K

Related Experiment Videos

Last Updated: Sep 6, 2025

Synthetic Antigen Controls for Immunohistochemistry
09:30

Synthetic Antigen Controls for Immunohistochemistry

Published on: August 23, 2021

2.6K
Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.7K
Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
20:24

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study

Published on: January 31, 2014

16.6K

Area of Science:

  • Econometrics
  • Statistical Modeling
  • Causal Inference

Background:

  • Uncertainty quantification is crucial for interpreting synthetic control (SC) method results.
  • Existing SC methods often lack rigorous uncertainty estimation.
  • Addressing uncertainty is vital for reliable causal inference.

Purpose of the Study:

  • To develop conditional prediction intervals within the SC framework.
  • To provide finite-sample probability guarantees for these intervals.
  • To enable covariate adjustment and handle non-stationary data in SC.

Main Methods:

  • Developed conditional prediction intervals accounting for two sources of randomness: SC weight construction and post-treatment error.
  • Proposed a simulation-based approach for implementation.
  • Utilized finite-sample probability bounds for sensitivity analysis.

Main Results:

  • Demonstrated the ability to provide finite-sample probability guarantees for prediction intervals.
  • Showcased the method's applicability with covariate adjustment and non-stationary data.
  • Empirical applications and simulations confirmed numerical performance.

Conclusions:

  • The proposed method offers a principled way to quantify uncertainty in SC analyses.
  • Conditional prediction intervals enhance the reliability of causal effect estimation.
  • Software packages in Python, R, and Stata are available for practical implementation.