Unbiased estimation of the Hessian for partially observed diffusions
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Updated: Sep 6, 2025

Synthesis of Cyclic Polymers and Characterization of Their Diffusive Motion in the Melt State at the Single Molecule Level
Published on: September 26, 2016
Neil K Chada1, Ajay Jasra1, Fangyuan Yu1
1Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology, Thuwal, 23955-6900, Saudi Arabia.
Abstract:
In this article, we consider the development of unbiased estimators of the Hessian, of the log-likelihood function with respect to parameters, for partially observed diffusion processes. These processes arise in numerous applications, where such diffusions require derivative information, either through the Jacobian or Hessian matrix. As time-discretizations of diffusions induce a bias, we provide an unbiased estimator of the Hessian. This is based on using Girsanov's Theorem and randomization schemes developed through Mcleish (2011 Monte Carlo Methods Appl. 17, 301-315 (doi:10.1515/mcma.2011.013)) and Rhee & Glynn (2016 Op. Res. 63, 1026-1043). We demonstrate our developed estimator of the Hessian is unbiased, and one of finite variance. We numerically test and verify this by comparing the methodology here to that of a newly proposed particle filtering methodology. We test this on a range of diffusion models, which include different Ornstein-Uhlenbeck processes and the Fitzhugh-Nagumo model, arising in neuroscience.
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