Drug-induced acute transient myopia with retinal folds

A patient was seen with acute bilateral transient myopia, shallowing of the anterior chamber, and radiating perimacular folds. This was believed to be a drug reaction. A fluorescein angiogram was performed which showed no retinal edema. A number of pathophysiologic mechanisms have been proposed for acute transient myopia, but the findings in this patient support ciliary body swelling as the cause of the changes in the eye. This swelling of the ciliary body results in a forward rotation of the lens-iris diaphragm and the vitreous, which causes both the myopia and the retinal folds.