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Diffuse large B-cell lymphoma associated ileocecal intussusception in adulthood.
Summary
Adult intussusception is rare, often linked to malignancy. Diffuse large B-cell lymphoma is a key cause of ileocecal intussusception, requiring prompt diagnosis and treatment.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Adult intussusception is a rare condition, comprising 5% of all intussusception cases and 1-5% of bowel obstructions.
- Malignant conditions are identified in nearly half of adult intussusception cases, necessitating treatment of the underlying pathology.
Observation:
- A 52-year-old male presented with a 6-month history of right lower abdominal pain, significant weight loss, and a palpable abdominal mass.
- Colonoscopy revealed an ileocecal mass, leading to a laparoscopic right hemicolectomy.
- Histopathology and immunohistochemistry confirmed diffuse large B-cell lymphoma.
Findings:
- Multi-slice spiral CT scans diagnosed intussusception preoperatively, showing characteristic signs like the target sign.
- Post-surgical analysis revealed diffuse large B-cell lymphoma as the cause of ileocecal intussusception.
- The patient achieved complete remission following RCHOP chemotherapy.
Implications:
- Diffuse large B-cell lymphoma is identified as a primary cause of adult ileocecal intussusception.
- Abdominal CT is crucial for accurate preoperative diagnosis of adult intussusception.
- Early diagnosis and treatment of underlying malignancies are vital in managing adult intussusception.
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