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Plasmonic metal oxides and their biological applications
Yihong Hu1, Bao Yue Zhang1,2, Farjana Haque1
1School of Engineering, RMIT University, Melbourne, Victoria, 3000, Australia. jianzhen.ou@rmit.edu.au.
Materials Horizons
|June 30, 2022
Summary
Plasmonic metal oxides, engineered with dopants and defects, offer tunable optical properties for biological applications. These cost-effective, biocompatible materials show promise for advanced medical devices.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Metal oxides modified with dopants and defects exhibit localized surface plasmon resonance (LSPR) across broad optical wavelengths.
- Plasmonic metal oxides are increasingly researched for biological applications due to their cost-efficiency, tunable properties, and biocompatibility compared to noble metals.
Purpose of the Study:
- To review the fundamental principles of plasmonics in dopant/defect-enabled metal oxides.
- To discuss advancements in dopant incorporation and defect generation strategies.
- To summarize the applications of plasmonic metal oxides in biological therapy, imaging, and sensing.
Main Methods:
- Explication of the origin of plasmonics using the Mie-Gans model.
- Critical discussion of in situ and ex situ methods for dopant and defect engineering.
- Summarization of research progress and implementation in biological fields.
Main Results:
- Dopant/defect engineering enables tunable LSPR in metal oxides.
- Various in situ and ex situ approaches facilitate material modification.
- Plasmonic metal oxides demonstrate significant potential in therapeutic, imaging, and sensing applications.
Conclusions:
- Plasmonic metal oxides represent a promising class of materials for next-generation biomedical devices.
- The unique properties driven by dopant/defect plasmonics can lead to novel functionalities.
- This review provides guidance for developing advanced human health monitoring and therapeutic tools.

