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Updated: Jun 28, 2026

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Multiple Subcutaneous 18F-FDG-avid Granulomas Due to Enoxaparin Injection

Özge Erol Fenercioğlu1, Nurhan Ergül1, Ediz Beyhan1

  • 1University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey.

Molecular Imaging and Radionuclide Therapy
|June 30, 2022
PubMed

A 67-year-old female patient with metastatic gastric adenocarcinoma was referred to 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for restaging. PET/CT revealed liver metastasis and the patient received six-cycles of chemotherapy. On control 18F-FDG PET/CT the liver lesion disappeared but newly formed multiple foci of increased uptake in the subcutaneous adipose tissues of the abdominal wall were detected. The uptake was related to nodular lesions resulting from an idiosyncratic reaction to enoxaparin and from local trauma through repeated injections.

Keywords:
18F-FDG PET/CTEnoxaparingranuloma

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