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Updated: Sep 6, 2025

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
A cone beam computed tomography study based on three-dimensional cephalometric analysis of relationships between the
Caitian Teng1, Junwei Zhu1, Huifang Wang2
1Nanjing Stomatological Hospital, Medical School of Nanjing University, 210008 Nanjing, China.
Objective:
The aim of this study was to use the cone beam computed tomography (CBCT) to study the relationships between the lip-line and mandible deformity.
Design:
CBCT data of 20 patients with jaw deformity (experimental group) and 20 patients without mandible deformity (control group) were selected. Use three-dimensional cephalometry to measure the reconstructed images of CBCT data simulated by the Materialise Interactive Medical Image Control System (Mimics), mark the related points, lines and planes of the three-dimensional craniomaxillofacial structure, and measure relevant distances and angles. The T-test, Pearson correlation analysis and Linear regression were used to analyze the characteristics of the lip-line and jaw deformity.
Results:
There was a significant difference in the lip-line between mandible deformity group and control group. Significant positive correlations could been found among the lip-line cant, the occlusal plane cant, the mandibular plane cant and the degree of mandible deformity (r=0.964, 0.942, 0.611, P < 0.01). A linear relationship was found between the left lip-line cant Y and the menton deviation X [the mandible deflection to the right was defined as positive, and the left lip-line below frankfort horizontal was viewed as positive] as Y= 0.340 + 0.505X.
Conclusions:
The lip-line of patients with jaw deformity was inclined, and the lip-line cant was positively correlated with the degree of mandible deformity, and there was a certain linear relationship between the two, which could provide a theoretical reference for clinicians to diagnose and treat patients with mandible deformity.

