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Updated: Sep 6, 2025

Diagnostic Ultrasound Imaging of Mouse Diaphragm Function
Published on: April 21, 2014
Ultrasound imaging of diaphragmatic motion
Lauren A May1,2, Monica Epelman3,4, Oscar M Navarro5,6
1Department of Radiology, Nemours Children's Hospital, Wilmington, DE, USA.
Abstract:
The diaphragm is the key muscle of respiration, especially in infants. Diaphragmatic dysfunction and paralysis can have significant implications for medical management and treatment, and they can be challenging to diagnose by clinical parameters alone. Multiple imaging modalities are useful for assessing the diaphragm, but US - specifically M-mode US - offers several distinct advantages and few limitations compared to fluoroscopy, radiography, CT and MRI. The purpose of this manuscript is to discuss the pathophysiology of the diaphragm, review common indications for dynamic diaphragmatic US, describe optimal imaging technique, and discuss how to avoid imaging pitfalls.
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