Related Experiment Video
Updated: Sep 6, 2025

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
The baroreceptor reflex brought to life outside the classroom - an e-learning based asynchronous laboratory class
Tobias Heinrich1, Susanne Sehner2, Isabel Wageringel1,3
1Department of Cellular and Integrative Physiology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
This study shows that an e-learning laboratory class effectively teaches the baroreceptor reflex (BRR) using a modified Active Standing Test (AST) without medical equipment. Students achieved accurate heart rate responses, demonstrating the feasibility and success of this digital approach for cardiovascular physiology education.
Area of Science:
- Physiology
- Medical Education
- E-learning
Background:
- E-learning offers flexible, self-paced laboratory classes, enhancing traditional in-classroom settings.
- The baroreceptor reflex (BRR) is a key cardiovascular process typically taught using an Active Standing Test (AST).
- This study explored transforming the BRR laboratory class into an asynchronous e-learning format for unsupervised students.
Purpose of the Study:
- To assess the feasibility of an e-learning based asynchronous laboratory class on the baroreceptor reflex (BRR).
- To evaluate if untrained, non-supervised students could perform a modified Active Standing Test (AST) without medical equipment.
- To determine the effectiveness of digital materials in teaching cardiovascular physiology concepts.
Main Methods:
- Modified the conventional Active Standing Test (AST) by excluding blood pressure measurements.
- Integrated the modified AST into interactive digital material for independent student learning.
- Implemented the e-learning class in human medicine, dental medicine, midwifery, and pharmacy curricula, collecting data via an audience response system.
Main Results:
- 217 students completed the class, reporting a mean heart rate (HR) rise of ~20 bpm (~30%) during standing, consistent with textbook data.
- High feasibility reported, with ~80% of students experiencing no technical issues.
- Students reported high satisfaction (4.4/5 Likert scale), and HR data showed consistency across subgroups.
Conclusions:
- An e-learning asynchronous laboratory class effectively teaches the baroreceptor reflex (BRR) using a modified, non-supervised Active Standing Test (AST).
- The digital format, focusing on HR measurements, is feasible and well-received by students across various healthcare curricula.
- This approach broadens access to fundamental cardiovascular physiology concepts through adaptable and accessible e-learning.
Related Concept Videos
Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:
Assessment of blood pressure in brachial artery(two-step method)

