Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-term Potentiation01:25

Long-term Potentiation

2.9K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
2.9K
Integration of Synaptic Events01:28

Integration of Synaptic Events

2.1K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
2.1K
MOSFET: Enhancement Mode01:22

MOSFET: Enhancement Mode

470
Enhancement-mode MOSFETs are pivotal components in electronics, distinguished by their capacity to act as highly efficient switches. They are part of the larger family of metal-oxide Semiconductor Field-Effect Transistors (MOSFETs). They are available in two types: p-channel and n-channel, each tailored to specific polarity operations.
In their basic form, enhancement-mode MOSFETs are typically non-conductive when the gate-source voltage (Vgs) is zero. This default 'off' state means no...
470
Chemical Synapses01:26

Chemical Synapses

3.2K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Performance Infrared Photodetectors Based on Graphene Nanoribbon Vertical Heterojunctions via Dissociated Double-Walled Carbon Nanotubes.

Nanomaterials (Basel, Switzerland)·2026
Same author

Mechanism of the electrochemical hydrogenation of graphene.

Nature communications·2025
Same author

Enhancement in Performance and Reliability of Fully Transparent a-IGZO Top-Gate Thin-Film Transistors by a Two-Step Annealing Treatment.

Nanomaterials (Basel, Switzerland)·2025
Same author

Effects of Ion Valence States and Radii on the Performance of Solid-State PEDOT:PSS Electrochromic Devices.

ACS applied materials & interfaces·2024
Same author

Light-Triggered Anti-ambipolar Transistor Based on an In-Plane Lateral Homojunction.

Nano letters·2024
Same author

Electrolyte-gated amorphous IGZO transistors with extended gates for prostate-specific antigen detection.

Lab on a chip·2024

Related Experiment Video

Updated: Sep 6, 2025

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

7.0K

Sputtered Electrolyte-Gated Transistor with Temperature-Modulated Synaptic Plasticity Behaviors.

Yang Ming Fu1, Hu Li2, Tianye Wei1

  • 1Department of Electrical and Electronic Engineering, The University of Manchester, Manchester M13 9PL, U.K.

ACS Applied Electronic Materials
|July 5, 2022
PubMed
Summary

Temperature significantly impacts indium-gallium-zinc oxide transistors used for neuromorphic computing. Higher temperatures alter synaptic plasticity, affecting device performance and learning capabilities.

More Related Videos

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

11.7K
Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
08:07

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

Published on: March 9, 2019

7.9K

Related Experiment Videos

Last Updated: Sep 6, 2025

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

7.0K
Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

11.7K
Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
08:07

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

Published on: March 9, 2019

7.9K

Area of Science:

  • Materials Science
  • Electronics Engineering
  • Neuroscience

Background:

  • Semiconductor devices are sensitive to temperature variations.
  • Indium-gallium-zinc oxide (IGZO) thin-film transistors (TFTs) are promising for neuromorphic applications.
  • Electrolyte-gated transistors (EGTs) offer unique synaptic functionalities.

Purpose of the Study:

  • To investigate the temperature-dependent synaptic plasticity of IGZO TFTs.
  • To understand how temperature affects the electrical characteristics and synaptic behaviors of EGTs.
  • To propose a physical model explaining these temperature effects.

Main Methods:

  • Fabrication of IGZO TFTs gated with sputtered SiO2 electrolytes.
  • Characterization of transistor electrical properties at varying temperatures (303-323 K).
  • Analysis of synaptic behaviors under single and multiple gate pulses.

Main Results:

  • Electrolyte capacitance decreased, while mobility and negative threshold voltage shift increased with temperature.
  • Post-synaptic current (PSC) at resting state increased with temperature.
  • PSC signal amplitude and retention time decreased under pulsed gate stimulation as temperature rose.

Conclusions:

  • A physical model involving ion drifting, ionic-electronic coupling, and diffusion explains the observed temperature dependence.
  • Temperature modulation of synaptic behavior was conceptually demonstrated, showing potential for learning and memory.
  • This research provides insights for developing temperature-resilient EGT-based neuromorphic systems.