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Updated: Sep 6, 2025
06:45
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
517
Antibacterial biomaterials for skin wound dressing
Yuqing Liang1,2, Yongping Liang1,2, Hualei Zhang1,2
1Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an 710049, China.
Asian Journal of Pharmaceutical Sciences
|July 5, 2022
Summary
Novel antibacterial wound dressings integrate bioactive agents into biomaterials to combat infection and improve skin healing. This review details antibacterial agents and biomaterial fabrication for advanced wound care.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Infectious Diseases
Background:
- Bacterial infections and rising antibiotic resistance pose significant threats to human health and wound healing.
- Effective wound management requires strategies that address bacterial contamination and promote tissue regeneration.
Purpose of the Study:
- To comprehensively review antibacterial biomaterials used as wound dressings.
- To summarize recent advances in antibacterial agents and biomaterial fabrication for skin tissue engineering.
Main Methods:
- Review of literature on antibacterial agents (antibiotics, nanoparticles, cationic organic agents).
- Discussion of biomaterial fabrication techniques (films, hydrogels, nanofibers, sponges, foams, 3D scaffolds).
Main Results:
- Various antibacterial agents and their mechanisms are summarized.
- Different biomaterial structures and their suitability for skin regeneration are elaborated.
Conclusions:
- Antibacterial wound dressings are crucial for enhancing wound healing and combating resistance.
- Further research into elegant design and refinement of these dressings is needed.
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