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Updated: Sep 5, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
ACG-CAG provided suggestions for periendoscopic management of anticoagulants and antiplatelets
David R Lichtenstein1, Neal D Dharmadhikari1
1Boston University School of Medicine, Boston, Massachusetts, USA (D.R.L., N.D.D.).
Insights
This guideline provides recommendations for managing anticoagulant and antiplatelet medications during gastrointestinal bleeding and endoscopic procedures. It aims to reduce bleeding risk while considering thrombotic risks for patients.
Area of Science:
- Gastroenterology
- Clinical Practice Guidelines
- Pharmacology
Background:
- Acute gastrointestinal (GI) bleeding is a common medical emergency.
- Management of anticoagulants and antiplatelets in patients with GI bleeding is complex.
- Balancing bleeding risk and thrombotic risk is crucial.
Purpose of the Study:
- To provide evidence-based recommendations for the management of anticoagulants and antiplatelets.
- To guide clinicians during acute GI bleeding.
- To inform decisions in the periendoscopic period.
Main Methods:
- Systematic review of existing literature.
- Development of clinical practice guidelines by expert consensus.
- Formulation of recommendations based on risk-benefit analysis.
Main Results:
- Specific strategies for continuing, holding, or bridging anticoagulants and antiplatelets.
- Recommendations tailored to different types of GI bleeding and endoscopic procedures.
- Emphasis on individualized patient assessment.
Conclusions:
- The guideline offers a structured approach to managing antithrombotic therapy in GI bleeding.
- Adherence to these recommendations can optimize patient outcomes.
- These guidelines are essential for gastroenterologists and other healthcare providers.
Source Citation:
Abraham NS, Barkun AN, Sauer BG, et al. American College of Gastroenterology-Canadian Association of Gastroenterology clinical practice guideline: management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period. Am J Gastroenterol. 2022;117:542-58. 35297395.
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