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Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Related Experiment Video

Updated: Sep 5, 2025

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography
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Special Section Guest Editorial: Hard X-Ray Tomography with Micrometer Resolution.

Bert Müller1, Stuart R Stock2, Ge Wang3

  • 1University of Basel, Biomaterials Science Center, Allschwil, Switzerland.

Journal of Medical Imaging (Bellingham, Wash.)
|July 5, 2022
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Summary
This summary is machine-generated.

This special section showcases advances in hard X-ray tomography, providing micrometer-level resolution imaging. It offers a glimpse into this specialized field of advanced imaging techniques.

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Area of Science:

  • Physics
  • Materials Science
  • Engineering

Background:

  • Hard X-ray tomography is a powerful non-destructive imaging technique.
  • Achieving micrometer resolution is crucial for detailed material analysis.

Purpose of the Study:

  • To present a collection of articles on hard X-ray tomography.
  • To highlight advancements in micrometer-resolution imaging capabilities.

Main Methods:

  • Utilizing hard X-ray sources for high penetration depth.
  • Employing tomographic reconstruction algorithms for 3D imaging.
  • Focusing on techniques achieving micrometer spatial resolution.

Main Results:

  • Demonstration of micrometer-level resolution in hard X-ray tomography.
  • Presentation of diverse applications across scientific disciplines.
  • Showcasing the state-of-the-art in this niche imaging area.

Conclusions:

  • Hard X-ray tomography with micrometer resolution is a rapidly developing field.
  • This special section captures the current progress and potential of this technology.
  • Further advancements promise enhanced capabilities for scientific discovery.