Recent Progress in Microalgal Squalene Production and Its Cosmetic Application

Area of Science:

• Biochemistry
• Marine Biotechnology
• Cosmetic Science

Background:

• Squalene is a bioactive terpenoid naturally produced by animals and plants, comprising 12% of human sebum.
• It possesses anti-inflammatory, detoxifying, moisturizing, and antioxidant properties, crucial for skin health.
• Age-related decline in squalene production necessitates supplementation through external products.

Purpose of the Study:

• To review recent advancements in squalene production and applications.
• To explore microalgae as a sustainable alternative to shark-derived squalene.
• To evaluate the cosmetic potential of microalgal squalene.

Main Methods:

• Literature review of squalene producers and production methods.
• Analysis of microalgal strains for squalene biosynthesis.
• Assessment of cosmetic properties and efficacy of squalene.

Main Results:

• Sharks are a primary but unsustainable source of squalene, leading to conservation concerns.
• Microalgae are identified as promising sustainable sources for squalene production.
• Squalene derived from microalgae demonstrates significant potential for cosmetic applications.

Conclusions:

• Microalgal squalene presents a viable, ethical alternative to shark-derived squalene.
• Further research into microalgal cultivation and extraction can meet market demands.
• Squalene's beneficial properties support its continued use in cosmetic and pharmaceutical industries.