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[Massive breast involvement in Burkitt's lymphoma].

D Plantaz, C Bachelot, J F Dyon

    Archives Francaises De Pediatrie
    |March 1, 1987
    PubMed
    Summary

    This case report details an exceptional instance of Burkitt's lymphoma affecting both breasts in a young girl. Successful chemotherapy led to a complete remission, highlighting effective treatment options for this rare presentation.

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    Area of Science:

    • Oncology
    • Pediatric Hematology/Oncology
    • Cancer Biology

    Background:

    • Burkitt's lymphoma is an aggressive non-Hodgkin lymphoma with rapid proliferation.
    • Breast involvement in pediatric lymphomas is rare, particularly as a primary or extensive manifestation.

    Observation:

    • A 13-year-old female presented with massive bilateral breast involvement secondary to Burkitt's lymphoma.
    • The disease was classified as extensive, stage IV, with significant organ involvement but no central nervous system (CNS) metastasis.

    Findings:

    • The patient received chemotherapy using the LMB 84 regimen.
    • The treatment resulted in a complete cure, with the patient remaining disease-free for 18 months post-therapy.

    Implications:

    • This case underscores the possibility of extensive breast involvement in pediatric Burkitt's lymphoma.
    • Early and aggressive chemotherapy, such as LMB 84, can achieve complete remission even in advanced stages.
    • Highlights the importance of considering rare presentations in the differential diagnosis of pediatric breast masses.

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