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Updated: Sep 5, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Clinical experience regarding the diagnostic value of segment-by-segment coronary computed tomography angiography in
Rafael Mansur Souto1, Alair Augusto Sarmet Moreira Damas Dos Santos1, Marcelo Souto Nacif1
1Hospital Universitário Antônio Pedro - Universidade Federal Fluminense (HUAP-UFF), Niterói, RJ, Brazil.
Objective:
To compare the degree of coronary stenosis (≥ 50% luminal narrowing) determined by coronary computed tomography angiography (CCTA) with that determined by invasive coronary angiography (ICA), using segment-by-segment analysis.
Materials And Methods:
This was a retrospective study of the records of patients who underwent CCTA and ICA between January 2014 and June 2018 at a general hospital in Brazil. Receiver operating characteristic curve analysis was applied, and the areas under the curve were used in order to assess the overall accuracy of the methods.
Results:
The degree of coronary stenosis was evaluated in a total of 844 arterial segments. The diagnostic performance of CCTA was good, with a sensitivity of 82.3%, a specificity of 96.4%, and a negative predictive value of 97.7% (95% CI: 96.5-98.5). In the segment-by-segment analysis, CCTA had excellent accuracy for the left main coronary artery and for other segments.
Conclusion:
In clinical practice at general hospitals, CCTA appears to have diagnostic performance comparable to that of ICA.
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