Related Experiment Video

Updated: Sep 5, 2025

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
12:43

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

Published on: February 21, 2011

34.9K

Characterizing Pediatric Bilateral Vocal Fold Dysfunction: Analysis with the Pediatric Health Information System

Aryan D Shay1, Isabella Zaniletti2, Kyle P Davis1

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas, U.S.A.

The Laryngoscope
|July 7, 2022
PubMed

Insights

Pediatric bilateral vocal fold dysfunction impacts many children, with gastrointestinal issues and tracheostomy improving survival. Tracheostomy, however, increases costs and comorbidities.

Area of Science:

  • Pediatric Otolaryngology
  • Pulmonology
  • Health Services Research

Background:

  • Bilateral vocal fold dysfunction (BVFD) is a complex condition in children.
  • Characterizing BVFD is crucial for understanding its impact on pediatric healthcare.

Purpose of the Study:

  • To characterize pediatric bilateral vocal fold dysfunction (BVFD).
  • To examine factors influencing inpatient mortality in pediatric BVFD cases.

Main Methods:

  • Retrospective cohort analysis of pediatric patients diagnosed with BVFD (2008-2020).
  • Utilized data from the Pediatric Health Information System.
  • Employed univariate and multivariate Cox proportional hazard models.

Main Results:

  • Analyzed 4799 hospitalizations for 2395 pediatric patients with BVFD.
  • Inpatient mortality was 2.9%; 61.1% had comorbid respiratory conditions.
  • Gastrointestinal comorbidities (HR: 0.29) and tracheostomy (HR: 0.21) were favorable prognostic indicators for survival.

Conclusions:

  • This study is the largest cohort analysis of pediatric BVFD.
  • Gastrointestinal comorbidities and tracheostomy are favorable prognostic indicators for survival.
  • Tracheostomy is linked to increased hospital costs, comorbidities, and gastrostomy placement.
Abstract

Keywords:
PHISbilateral vocal fold dysfunctionmortalitypediatrictracheostomy

More Related Videos

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing07:22

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

640
Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

8.6K

Related Concept Videos

Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
704
Respiratory System Abnormal Finding I: Inspection and Percussion01:30

Respiratory System Abnormal Finding I: Inspection and Percussion

Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
426
Physical Assessment of the Respiratory Tract IV: Auscultation01:28

Physical Assessment of the Respiratory Tract IV: Auscultation

Auscultation is a crucial component of the physical assessment of the respiratory tract. It offers valuable insights into airflow through the bronchial tree and potential lung obstructions. This process involves careful listening to breath, voice, and adventitious sounds, which can reveal a wealth of information about a patient's respiratory health.
Breath Sounds
Breath sounds are categorized into vesicular, bronchovesicular, and bronchial.
679
Larynx01:21

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
2.0K
Physical Assessment of the Respiratory Tract I: Health History01:28

Physical Assessment of the Respiratory Tract I: Health History

Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
384
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
430