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Characterizing Pediatric Bilateral Vocal Fold Dysfunction: Analysis with the Pediatric Health Information System
Aryan D Shay1, Isabella Zaniletti2, Kyle P Davis1
1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas, U.S.A.
The Laryngoscope
|July 7, 2022
Summary
Pediatric bilateral vocal fold dysfunction impacts many children, with gastrointestinal issues and tracheostomy improving survival. Tracheostomy, however, increases costs and comorbidities.
Area of Science:
- Pediatric Otolaryngology
- Pulmonology
- Health Services Research
Background:
- Bilateral vocal fold dysfunction (BVFD) is a complex condition in children.
- Characterizing BVFD is crucial for understanding its impact on pediatric healthcare.
Purpose of the Study:
- To characterize pediatric bilateral vocal fold dysfunction (BVFD).
- To examine factors influencing inpatient mortality in pediatric BVFD cases.
Main Methods:
- Retrospective cohort analysis of pediatric patients diagnosed with BVFD (2008-2020).
- Utilized data from the Pediatric Health Information System.
- Employed univariate and multivariate Cox proportional hazard models.
Main Results:
- Analyzed 4799 hospitalizations for 2395 pediatric patients with BVFD.
- Inpatient mortality was 2.9%; 61.1% had comorbid respiratory conditions.
- Gastrointestinal comorbidities (HR: 0.29) and tracheostomy (HR: 0.21) were favorable prognostic indicators for survival.
Conclusions:
- This study is the largest cohort analysis of pediatric BVFD.
- Gastrointestinal comorbidities and tracheostomy are favorable prognostic indicators for survival.
- Tracheostomy is linked to increased hospital costs, comorbidities, and gastrostomy placement.
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